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Article

Targeted next-generation sequencing of candidate genes reveals novel mutations in patients with dilated cardiomyopathy.

International journal of molecular medicine - 1 Dec 2015

Zhao Yue, Feng Yue, Zhang Yun-Mei, Ding Xiao-Xue, Song Yu-Zhu, Zhang A-Mei, Liu Li, Zhang Hong, Ding Jia-Huan, Xia Xue-Shan

Abstract excerpt

Dilated cardiomyopathy (DCM) is a major cause of sudden cardiac death and heart failure, and it is characterized by genetic and clinical heterogeneity, even for some patients with a very poor clinical prognosis; in the majority of cases, DCM necessitates a heart transplant. Genetic mutations have long been considered to be associated with this disease. At present, mutations in over 50 genes related to DCM have...

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Source

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Identifiers

PMID: 26458567
DOI: 10.3892/ijmm.2015.2361
PMCID: PMC4678153

Genes

MYBPC3
MYH6
DES
MYH7
MYL3
MYPN
TNNT2
RBM20
TNNC1
VCL
ACTC1
LMNA
TNNI3
TPM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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