Article
TNNT2 gene polymorphisms are associated with susceptibility to idiopathic dilated cardiomyopathy in the Han Chinese population.
BioMed research international - 1 Jan 2013
Li Xiaoping, Wang Huan, Luo Rong, Gu Haiyong, Zhang Channa, Zhang Yu, Hui Rutai, Wu Xiushan, Hua Wei
Abstract excerpt
BACKGROUND: Idiopathic dilated cardiomyopathy (DCM) is characterized by ventricular chamber enlargement and systolic dysfunction. The pathogenesis of DCM remains uncertain, and the TNNT2 gene is potentially associated with DCM. To assess the role of TNNT2 in DCM, we examined 10 tagging single nucleotide polymorphisms (SNPs) in the patients. METHODS: A total of 97 DCM patients and 189 control subjects were...
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