Article
Analysis of drug resistance marker genes of Plasmodium falciparum after implementation of artemisinin-based combination therapy in Pune district, India.
Journal of biosciences - 1 Jan 2021
Ozarkar Aarti, Kanyal Abhishek, Dass Swati, Deshpande Prakash, Deobagkar Deepti, Karmodiya Krishanpal
Abstract excerpt
The global emergence and spread of malaria parasites resistant to antimalarial drugs is a major problem in malaria control and elimination. In this study, samples from Pune district were characterized to determine prevalence of molecular markers of resistance to chloroquine (pfcrt codons C72S, M74I, N75E, K76T and pfmdr-1 N86Y, Y184F), pyrimethamine (pfdhfr C50R, N51I, C59R, S108N), sulfadoxine (pfdhps, S436A,...
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