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Article

Decoding disease: from genomes to networks to phenotypes.

Nature reviews. Genetics - 1 Dec 2021

Wong Aaron K, Sealfon Rachel S G, Theesfeld Chandra L, Troyanskaya Olga G

Abstract excerpt

Interpreting the effects of genetic variants is key to understanding individual susceptibility to disease and designing personalized therapeutic approaches. Modern experimental technologies are enabling the generation of massive compendia of human genome sequence data and associated molecular and phenotypic traits, together with genome-scale expression, epigenomics and other functional genomic data. Integrative...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34341555
DOI: 10.1038/s41576-021-00389-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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