Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tbx15 Defines a Glycolytic Subpopulation and White Adipocyte Heterogeneity.

Diabetes - 1 Nov 2017

Lee Kevin Y, Sharma Rita, Gase Grant, Ussar Siegfried, Li Yichao, Welch Lonnie, Berryman Darlene E, Kispert Andreas, Bluher Matthias, Kahn C Ronald

Abstract excerpt

Tbx15 is a member of the T-box gene family of mesodermal developmental genes. We have recently shown that Tbx15 plays a critical role in the formation and metabolic programming of glycolytic myofibers in skeletal muscle. Tbx15 is also differentially expressed among white adipose tissue (WAT) in different body depots. In the current study, using three independent methods, we show that even within a single WAT...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Body Weight
Share to Cell Line

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation

Share to Glycolysis

Share to Hexokinase

Share to Mice, Inbred C57BL

Share to Subcutaneous Fat

Share to T-Box Domain Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 28847884
DOI: 10.2337/db17-0218
PMCID: PMC5652605

Genes

TBX15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tbx15 Defines a Glycolytic Subpopulation and White Adipocyte Heterogeneity.PMID 28847884Read ↗

TBX15 regulates a network of immune response genes in adipose tissue and alters fat mass and depot weight in heterozygous knockout miceSemantic proximity Read ↗

Identification of TBX15 as an adipose master trans regulator of abdominal obesity genesSemantic proximity Read ↗

An essential role for Tbx15 in the differentiation of brown and "brite" but not white adipocytes.Semantic proximity Read ↗

Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cellsSemantic proximity Read ↗

KCTD15 Gene Expression Regulates Adipocyte Differentiation and Is Associated with Obesity in HumansSemantic proximity Read ↗

Adipose TBX1 regulates β-adrenergic sensitivity in subcutaneous adipose tissue and thermogenic capacity in vivoSemantic proximity Read ↗

Single-Nucleus Analysis of Human White Adipose Tissue Reveals Adipocyte Subsets with Distinct Metabolic ProfilesSemantic proximity Read ↗

Distinct populations of adipogenic and myogenic Myf5-lineage progenitors in white adipose tissuesSemantic proximity Read ↗

GDF15 inhibits early-stage adipocyte differentiation by enhancing HOP2 expression and suppressing C/EBPα expressionSemantic proximity Read ↗

A <i>Wars2</i> mutant mouse shows a sex and diet specific change in fat distribution, reduced food intake and depot-specific upregulation of WAT browningSemantic proximity Read ↗

A muscle hypertrophy-derived myokine reprograms the stromal vascular fractions differentiation towards thermogenic adipocytes in subcutaneous adipose tissueSemantic proximity Read ↗

ZBTB16 Overexpression Enhances White Adipogenesis and Induces Brown-Like Adipocyte Formation of Bovine White Intramuscular PreadipocytesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.