Article
Primary sclerosing cholangitis with moderately elevated serum-IgG4 - characterization and outcome of a distinct variant phenotype.
Liver international : official journal of the International Association for the Study of the Liver - 1 Dec 2021
Zhou Taotao, Lenzen Henrike, Dold Leona, Bündgens Bennet, Wedemeyer Heiner, Manns Michael P, Gonzalez-Carmona Maria A, Strassburg Christian P, Weismüller Tobias J
Abstract excerpt
BACKGROUND AND AIMS: Immunoglobulin G4-associated cholangitis (IAC) is characterized by distinctly elevated immunoglobulin G4 in serum (sIgG4) and responds well to corticosteroid therapy. Primary Sclerosing Cholangitis (PSC) is a progressive liver disease without causal treatment options usually not responding to immunosuppression. Increased serum levels of sIgG4 in patients with PSC, that do not meet criteria of...
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