Article
Inflammatory Bowel Disease and Primary Sclerosing Cholangitis: A Review of the Phenotype and Associated Specific Features.
Gut and liver - 15 Jan 2018
Palmela Carolina, Peerani Farhad, Castaneda Daniel, Torres Joana, Itzkowitz Steven H
Abstract excerpt
Primary sclerosing cholangitis (PSC) is a chronic, progressive cholestatic disease that is associated with inflammatory bowel disease (IBD) in approximately 70% of cases. Although the pathogenesis is still unknown for both diseases, there is increasing evidence to indicate that they share a common underlying predisposition. Herein, we review the epidemiology, diagnosis, disease pathogenesis, and specific clinical...
Topics
- Cholangitis, Sclerosing
- Colon
- Colorectal Neoplasms
- Female
- Humans
- Inflammatory Bowel Diseases
- Male
- Phenotype
- Risk Factors