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Article

Applicability of different cell line-derived dendritic cell-like cells in autophagy research.

Journal of immunological methods - 1 Oct 2021

Prins Marileen M C, van Roest Manon, Vermeulen Jacqueline L M, Tjabringa G Sandra, van de Graaf Stan F J, Koelink Pim J, Wildenberg Manon E

Abstract excerpt

BACKGROUND AND AIMS: Immortalized cell lines have been long used as substitute for ex vivo murine and human material, but exhibit features that are not found in healthy tissue. True human dendritic cells (DC) cannot be cultured or passaged as opposed to immortalized cell lines. Research in the fields of immunogenic responses and immunotolerance in DCs has increased over the last decade. Autophagy has gained...

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Identifiers

PMID: 34324891
DOI: 10.1016/j.jim.2021.113106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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