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Article

The RNA helicase Ddx52 functions as a growth switch in juvenile zebrafish.

Development (Cambridge, England) - 1 Aug 2021

Tseng Tzu-Lun, Wang Ying-Ting, Tsao Chang-Yu, Ke Yi-Teng, Lee Yi-Ching, Hsu Hwei-Jan, Poss Kenneth D, Chen Chen-Hui

Abstract excerpt

Vertebrate animals usually display robust growth trajectories during juvenile stages, and reversible suspension of this growth momentum by a single genetic determinant has not been reported. Here, we report a single genetic factor that is essential for juvenile growth in zebrafish. Using a forward genetic screen, we recovered a temperature-sensitive allele, pan (after Peter Pan), that suspends whole-organism...

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Identifiers

PMID: 34323273
DOI: 10.1242/dev.199578
PMCID: PMC8353168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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