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Article

Activation and gut-homing of peripheral T cells in HIV immunologic non-responders despite long term viral suppression.

PloS one - 1 Jan 2021

Rousseau Rodney K, Szadkowski Leah, Kovacs Colin M, Saikali Michael F, Nadeem Rabea, Malazogu Fat, Huibner Sanja, Cummins Carolyn L, Kaul Rupert, Walmsley Sharon L

Abstract excerpt

OBJECTIVE: Serious non-AIDS disease events (SNAE) are experienced disproportionately by immunologic non-responders (INRs), HIV-infected individuals who do not restore CD4 T cells in blood despite effective viral suppression. We aimed to characterize the inflammatory biomarker profile of the INR phenotype. METHODS: Blinded cross-sectional cohort study comparing markers of immune activation and gut homing between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34320023
DOI: 10.1371/journal.pone.0254149
PMCID: PMC8318285

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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