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Article

Alterations in Circulating T-Cell Subsets with Gut-Homing/Residency Phenotypes Associated with HIV-1 Status and Subclinical Atherosclerosis.

Cells - 4 Nov 2025

Moreira Gabriel Etiene, Dias Jonathan, Filali-Mouhim Abdelali, Caballero Ramon Edwin, Wiche Salinas Tomas Raul, Nayrac Manon, Chartrand-Lefebvre Carl, Routy Jean-Pierre, Durand Madeleine, El-Far Mohamed, Tremblay Cécile, Ancuta Petronela

Abstract excerpt

Antiretroviral therapy (ART) controls HIV-1 replication in people with HIV-1 (PWH), but intestinal integrity impairment persists and fuels microbial translocation and chronic immune activation, thus heightening the cardiovascular disease (CVD) risk. Here, we sought to identify novel immunological correlates of the HIV and CVD status in ART-treated PWH (HIV+; n = 42) and uninfected participants (HIV-; n = 40) of...

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Topics

Humans
Male
HIV Infections
HIV-1
Female
Atherosclerosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Middle Aged

T-Lymphocyte Subsets

Phenotype

Adult

Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 41227377
DOI: 10.3390/cells14211732
PMCID: PMC12607611

Genes

CD4
CCR6
CD69
CCR9

Provenance

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