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Article

Longitudinal change of genetic variations in cetuximab-treated metastatic colorectal cancer.

Cancer genetics - 1 Nov 2021

Kim Sun Young, Kim Kwoneel, Cho Su Han, Chun Sung-Min, Tak Eunyoung, Hong Yong Sang, Kim Jeong Eun, Kim Tae Won

Abstract excerpt

Recurrent gene mutations and copy number alterations in cancer patients are presumably associated with resistance to targeted therapy. In the present study, we assessed the gene mutations and copy number alterations that recurrently occurred in cetuximab-treated patients with metastatic colorectal cancer (mCRC). Targeted next-generation sequencing was performed in the tumor samples obtained pre- and postcetuximab...

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Identifiers

PMID: 34315006
DOI: 10.1016/j.cancergen.2021.06.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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