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Article

New genetic variations discovered in KRAS wild-type cetuximab resistant chinese colorectal cancer patients.

Molecular carcinogenesis - 1 May 2020

Jing Changwen, Wang Ting, Ma Rong, Cao Haixia, Wang Zhuo, Liu Siwen, Chen Dan, Zhang Junying, Wu Yang, Zhang Yuan, Wu Jianzhong, Feng Jifeng

Abstract excerpt

To perform a comprehensive genomic analysis of colorectal cancer (CRC) tumor to detect genetic variants and identify novel resistant mutations associated with cetuximab-resistance in CRC patients. A retrospective study was performed using whole exome sequencing (WES) to identify common genetic factors from 22 cetuximab-sensitive and 10 cetuximab-resistant patients. In all 10 cetuximab-resistant patients, we...

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PMID: 32141150
DOI: 10.1002/mc.23172

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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