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Article

Genetic Variation in miR-146a Is Not Associated with Susceptibility to IgA Nephropathy in Adults from a Chinese Han Population.

PloS one - 1 Jan 2015

Yang Bin, Wei Wei, Shi Yunying, Huang Zhuochun, Cai Bei, Zhang Junlong, Ying Binwu, Wang Lanlan

Abstract excerpt

BACKGROUND: MicroRNA 146a (miR-146a) is a 19 to 23 nucleotide long, small non-coding RNA with gene regulatory functions that has influence on the pathogenesis of many diseases. A single nucleotide polymorphism (rs2910164 C>G) in pre-miR-146a is correlated with the expression of miR-146a. The aim of this study was to perform an association analysis of rs2910164 with IgA nephropathy in adult patients from a Chinese...

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Identifiers

PMID: 26426696
DOI: 10.1371/journal.pone.0139554
PMCID: PMC4591345

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