Article
Association study of BDNF Val66Met gene polymorphism with bipolar disorder and lithium treatment response in Indian population.
Journal of psychopharmacology (Oxford, England) - 1 Dec 2021
Paul Pradip, Nadella Ravi Kumar, Sen Somdatta, Ithal Dhruva, Mahadevan Jayant, Reddy Y C Janardhan, Jain Sanjeev, Purushottam Meera, Viswanath Biju
Abstract excerpt
BACKGROUND: The association of the Val66Met (rs6265) polymorphism in the brain-derived neurotrophic factor (BDNF) gene with bipolar disorder (BD) and response to lithium treatment has been suggested, though inconsistently. The considerable diversity of allele frequency across different populations contributes to this. There is no data from South Asia till date. Hence, we examined the association of this...
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