Article
From Mesenchymal Stromal/Stem Cells to Insulin-Producing Cells: Immunological Considerations.
Frontiers in immunology - 1 Jan 2021
Refaie Ayman F, Elbassiouny Batoul L, Kloc Malgorzata, Sabek Omaima M, Khater Sherry M, Ismail Amani M, Mohamed Rania H, Ghoneim Mohamed A
Abstract excerpt
Mesenchymal stem cell (MSC)-based therapy for type 1 diabetes mellitus (T1DM) has been the subject matter of many studies over the past few decades. The wide availability, negligible teratogenic risks and differentiation potential of MSCs promise a therapeutic alternative to traditional exogenous insulin injections or pancreatic transplantation. However, conflicting arguments have been reported regarding the...
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