Article
Inclusion of ALKBH5 as a candidate gene for the susceptibility of autoimmune thyroid disease.
Advances in medical sciences - 1 Sept 2021
Song Rong-Hua, Zhao Jing, Gao Chao-Qun, Qin Qiu, Zhang Jin-An
Abstract excerpt
PURPOSE: RNA demethylase AlkB homolog 5 (ALKBH5) gene is pivotal in N6-methyladenosine (m6A) modification. Therefore, this study aimed to explore the potential relationship between polymorphisms of ALKBH5 gene and the development of autoimmune thyroid disease (AITD). MATERIAL AND METHODS: A case-control study of 979 AITD patients, including 620 Graves' disease (GD) and 359 Hashimoto's thyroiditis (HT), and 732...
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