Article
Mechanisms of autoimmune thyroid diseases: from genetics to epigenetics.
Annual review of pathology - 1 Jan 2014
Tomer Yaron
Abstract excerpt
Recent advances in our understanding of genetic-epigenetic interactions have unraveled new mechanisms underlying the etiology of complex autoimmune diseases. Autoimmune thyroid diseases (AITDs) are highly prevalent, affecting 1% to 5% of the population. The major AITDs include Graves disease (GD) and Hashimoto's thyroiditis (HT); although these diseases contrast clinically, their pathogenesis involves shared...
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