Allele-Specific Thresholds of Eluted Ligands for T-Cell Epitope Prediction.

Abstract excerpt

A common strategy for predicting candidate human leukocyte antigen class I T-cell epitopes is to use an affinity-based threshold of 500 nM. Although a 500 nM threshold across alleles effectively identifies most epitopes across alleles, findings showing that major histocompatibility complex repertoire sizes vary by allele indicate that using thresholds specific to individual alleles may improve epitope...

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• Share to Alleles
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• Share to HLA-A Antigens