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Article

HLA class I alleles are associated with peptide-binding repertoires of different size, affinity, and immunogenicity.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2013

Paul Sinu, Weiskopf Daniela, Angelo Michael A, Sidney John, Peters Bjoern, Sette Alessandro

Abstract excerpt

Prediction of HLA binding affinity is widely used to identify candidate T cell epitopes, and an affinity of 500 nM is routinely used as a threshold for peptide selection. However, the fraction (percentage) of peptides predicted to bind with affinities of 500 nM varies by allele. For example, of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24190657
DOI: 10.4049/jimmunol.1302101
PMCID: PMC3872965

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24190657-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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