Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Liver-Resident Bystander CD8+ T Cells Contribute to Liver Disease Pathogenesis in Chronic Hepatitis D Virus Infection.

Gastroenterology - 1 Nov 2021

Kefalakes Helenie, Horgan Xylia J, Jung Min Kyung, Amanakis Georgios, Kapuria Devika, Bolte Fabian J, Kleiner David E, Koh Christopher, Heller Theo, Rehermann Barbara

Abstract excerpt

BACKGROUND & AIMS: The hepatitis D virus (HDV) causes the most severe form of chronic hepatitis, often progressing to cirrhosis within 5 to 10 years. There is no curative treatment, and the mechanisms underlying the accelerated liver disease progression are unknown. METHODS: Innate and adaptive immune responses were studied in blood and liver of 24 patients infected with HDV and 30 uninfected controls by...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptive Immunity
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Degranulation

Share to Hepatitis Delta Virus

Share to Host-Pathogen Interactions

Share to Immunologic Memory

Share to Killer Cells, Natural

Share to NK Cell Lectin-Like Receptor Subfamily K

Source

Open in PubMed Open full text

Identifiers

PMID: 34302839
DOI: 10.1053/j.gastro.2021.07.027
PMCID: PMC10263257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Liver-Resident Bystander CD8+ T Cells Contribute to Liver Disease Pathogenesis in Chronic Hepatitis D Virus Infection.PMID 34302839Read ↗

Innate-like Cytotoxic Function of Bystander-Activated CD8+ T Cells Is Associated with Liver Injury in Acute Hepatitis ASemantic proximity Read ↗

Hepatitis D Virus-Specific CD8+ T Cells Have a Memory-Like Phenotype Associated With Viral Immune Escape in Patients With Chronic Hepatitis D Virus InfectionSemantic proximity Read ↗

Liver-resident CD8+ T cells in viral hepatitis: not always good guysSemantic proximity Read ↗

Intra-Hepatic Depletion of Mucosal-Associated Invariant T Cells in Hepatitis C Virus-Induced Liver Inflammation.Semantic proximity Read ↗

CD38+HLA-DR+CD8+ T Cells induced by IL-15 exert liver injury through NKG2D in chronic hepatitis B cirrhosisSemantic proximity Read ↗

Targeted impairment of innate antiviral responses in the liver of chronic hepatitis C patientsSemantic proximity Read ↗

Hepatic compartmentalization of exhausted and regulatory cells in HIV/HCV-coinfected patients.Semantic proximity Read ↗

Features and distribution of CD8 T cells with human leukocyte antigen class I-specific receptor expression in chronic hepatitis C.Semantic proximity Read ↗

IL-10 distinguishes a unique population of activated, effector-like CD8+ T cells in murine acute liver inflammation.Semantic proximity Read ↗

Natural killer cells: multifaceted players with key roles in hepatitis C immunity.Semantic proximity Read ↗

Tissue-resident memory T cells in chronic liver diseases: Phenotype, development and function.Semantic proximity Read ↗

Compromised function of natural killer cells in acute and chronic viral hepatitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.