Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL-10 distinguishes a unique population of activated, effector-like CD8+ T cells in murine acute liver inflammation.

Journal of leukocyte biology - 1 Apr 2017

Rood Julia E, Canna Scott W, Weaver Lehn K, Tobias John W, Behrens Edward M

Abstract excerpt

Immune-mediated liver injury is a central feature of hyperinflammatory diseases, such as hemophagocytic syndromes, yet the immunologic mechanisms underlying those processes are incompletely understood. In this study, we used the toll-like receptor 9 (TLR9)-mediated model of a hemophagocytic syndrome known as macrophage activation syndrome (MAS) to dissect the predominant immune cell populations infiltrating the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Antigens
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intercellular Signaling Peptides and Proteins

Share to Interferon-gamma

Share to Interleukin-10

Share to Lymphohistiocytosis, Hemophagocytic

Share to Toll-Like Receptor 9

Source

Open in PubMed Open full text

Identifiers

PMID: 28034913
DOI: 10.1189/jlb.3A0916-221RR
PMCID: PMC5346180

Genes

TLR9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL-10 distinguishes a unique population of activated, effector-like CD8+ T cells in murine acute liver inflammation.PMID 28034913Read ↗

Repeated TLR9 stimulation results in macrophage activation syndrome–like disease in miceSemantic proximity Read ↗

Tissue-resident memory T cells in chronic liver diseases: Phenotype, development and function.Semantic proximity Read ↗

Innate-like Cytotoxic Function of Bystander-Activated CD8+ T Cells Is Associated with Liver Injury in Acute Hepatitis ASemantic proximity Read ↗

CD4 <sup>+</sup> T cells promote fibrosis during metabolic dysfunction-associated steatohepatitisSemantic proximity Read ↗

Liver-Resident Bystander CD8+ T Cells Contribute to Liver Disease Pathogenesis in Chronic Hepatitis D Virus Infection.Semantic proximity Read ↗

Macrophage Phenotype and Function in Liver Disorder.Semantic proximity Read ↗

Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP.Semantic proximity Read ↗

NK cells in liver homeostasis and viral hepatitisSemantic proximity Read ↗

Leukocytes, Systemic Inflammation and Immunopathology in Acute-on-Chronic Liver Failure.Semantic proximity Read ↗

IFNγ initiates TLR9-dependent autoimmune hepatitis in DNase II deficient miceSemantic proximity Read ↗

Role of IRAK-M in alcohol induced liver injury.Semantic proximity Read ↗

T-cell activation profiles distinguish hemophagocytic lymphohistiocytosis and early sepsisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.