Article
Making Cardiomyocytes from Pluripotent Stem Cells.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Karagiannis Peter, Yoshida Yoshinori
Abstract excerpt
The ability to differentiate pluripotent stem cells to cardiomyocyte lineages (PSC-CMs) has opened the door to new disease models and innovative drug and cell therapies for the heart. Nevertheless, further advances in the differentiation protocols are needed to fulfill the promise of PSC-CMs. Obstacles that remain include deriving PSC-CMs with proper electromechanical properties, coalescing them into functional...
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