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Article

Missing Self-Induced Microvascular Rejection of Kidney Allografts: A Population-Based Study.

Journal of the American Society of Nephrology : JASN - 1 Aug 2021

Callemeyn Jasper, Senev Aleksandar, Coemans Maarten, Lerut Evelyne, Sprangers Ben, Kuypers Dirk, Koenig Alice, Thaunat Olivier, Emonds Marie-Paule, Naesens Maarten

Abstract excerpt

BACKGROUND: Circulating anti-HLA donor-specific antibodies (HLA-DSA) are often absent in kidney transplant recipients with microvascular inflammation (MVI). Missing self, the inability of donor endothelial cells to provide HLA I-mediated signals to inhibitory killer cell Ig-like receptors (KIRs) on recipient natural killer cells, can cause endothelial damage in vitro, and has been associated with HLA-DSA-negative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34301794
DOI: 10.1681/ASN.2020111558
PMCID: PMC8455279

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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