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Article

Phylogenetic variation in cortical layer II immature neuron reservoir of mammals.

eLife - 21 Jul 2020

La Rosa Chiara, Cavallo Francesca, Pecora Alessandra, Chincarini Matteo, Ala Ugo, Faulkes Chris G, Nacher Juan, Cozzi Bruno, Sherwood Chet C, Amrein Irmgard, Bonfanti Luca

Abstract excerpt

The adult mammalian brain is mainly composed of mature neurons. A limited amount of stem cell-driven neurogenesis persists in postnatal life and is reduced in large-brained species. Another source of immature neurons in adult brains is cortical layer II. These cortical immature neurons (cINs) retain developmentally undifferentiated states in adulthood, though they are generated before birth. Here, the occurrence,...

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Identifiers

PMID: 32690132
DOI: 10.7554/eLife.55456
PMCID: PMC7373429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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