Evaluation of a hybridization capture-based hereditary cancer panel for the ion semiconductor-based next-generation sequencing system.

Abstract excerpt

BACKGROUND: There is an unmet need to use the ThermoFisher Ion sequencing platform with a hybridization capture-based next-generation sequencing(NGS) panel. However, the analytical performance of combining an ion semiconductor-based sequencing system and a hybridization capture-based NGS panel has not been thoroughly evaluated. Therefore, we compared the analytic performance of Illumina's NextSeq and Ion S5 XL...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Predisposition to Disease
• Share to High-Throughput Nucleotide Sequencing