Article
Mutational profiling in acute lymphoblastic leukemia by RNA sequencing and chromosomal genomic array testing.
Cancer medicine - 1 Aug 2021
Yeung Cecilia, Qu Xiaoyu, Sala-Torra Olga, Woolston David, Radich Jerry, Fang Min
Abstract excerpt
BACKGROUND: Comprehensive molecular and cytogenetic profiling of acute lymphoblastic leukemia (ALL) is important and critical to the current standard of care for patients with B-acute lymphoblastic leukemia (B-ALL). Here we propose a rapid process for detecting gene fusions whereby FusionPlex RNA next-generation sequencing (NGS) and DNA chromosome genomic array testing (CGAT) are combined for a more efficient...
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