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Article

Polymorphisms at site 469 of B-RAF protein associated with skin melanoma may be correlated with dabrafenib resistance: An in silico study.

Journal of biomolecular structure & dynamics - 1 Jan 2022

Chatterjee Samadrita, Chakraborty Rajkumar, Hasija Yasha

Abstract excerpt

Melanoma is a type of skin cancer. Numerous genes and their proteins are strongly associated with melanoma susceptibility. This study aims to use an in silico method to identify genetic variants in the melanoma susceptibility gene. The COSMIC database was queried for genes and cross-referenced with three environment-gene interaction databases (EGP, SeattleSNPs and CTD) to identify shared genes. The majority of...

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Identifiers

PMID: 34278963
DOI: 10.1080/07391102.2021.1950571

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