Article
Efficacy and safety of dabrafenib-trametinib in the treatment of unresectable advanced/metastatic melanoma with BRAF-V600 mutation: A systematic review and network meta-analysis.
Dermatologic therapy - 1 Mar 2020
Garzón-Orjuela Nathaly, Prieto-Pinto Laura, Lasalvia Pieralessandro, Herrera Daniel, Castrillón Johanna, González-Bravo Diana, Castañeda-Cardona Camilo, Rosselli Diego
Abstract excerpt
The current systematic review aimed to evaluate and compare the efficacy and safety of dabrafenib-trametinib with those of other therapeutic alternatives in the treatment of patients with unresectable advanced/metastatic melanoma with BRAF-V600 mutation. The search was carried out on four databases up to July 2018. Two separate network meta-analyses (NMA) were performed using the frequentist method (random...
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