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Article

RORβ suppresses the stemness of gastric cancer cells by downregulating the activity of the Wnt signaling pathway

6 Jul 2021

Abstract excerpt

Gastric cancer (GC) is the third leading cause of cancer‑related mortality and the fifth most common type of cancer worldwide. GC stem cells (GCSCs) have been reported to be responsible for the malignant behavior of GC. However, the key molecular mechanism controlling GCSC function remains unclear. The present study aimed to investigate the function of retinoic acid‑related orphan receptor β (RORβ) in GC. The...

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PMID: 34278502
DOI: 10.3892/or.2021.8131

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