Plasticity of Mature B Cells Between Follicular and Classic Hodgkin Lymphomas: A Series of 22 Cases Expanding the Spectrum of Transdifferentiation.

doi:10.1097/PAS.0000000000001780

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Article

Plasticity of Mature B Cells Between Follicular and Classic Hodgkin Lymphomas: A Series of 22 Cases Expanding the Spectrum of Transdifferentiation.

The American journal of surgical pathology - 1 Jan 2022

Trecourt Alexis, Mauduit Claire, Szablewski Vanessa, Fontaine Juliette, Balme Brigitte, Donzel Marie, Laurent Camille, Sesques Pierre, Ghesquières Hervé, Bachy Emmanuel, Salles Gilles, Emile Jean-François, Chassagne-Clément Catherine, Genestier Laurent, Copie-Bergman Christiane, Traverse-Glehen Alexandra

Abstract excerpt

Follicular lymphoma and classic Hodgkin lymphoma can be associated in composite and/or sequential lymphomas. Common IGH and BCL2 rearrangements have already been identified between both contingents of these entities, but mutation profiles have not yet been investigated. The main objective of this study was to analyze the transdifferentiation process that may occur between Hodgkin and follicular contingents in...

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PMID: 34265801
DOI: 10.1097/PAS.0000000000001780

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