Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potential genetic mechanisms driving B/myeloid conversion in patients with follicular lymphoma and Langerhans cell neoplasms.

Leukemia & lymphoma - 1 Jun 2024

Tashakori Mehrnoosh, Medeiros L Jeffrey

Abstract excerpt

Transformation of follicular lymphoma (FL) to a Langerhans cell (LC) neoplasm is extremely uncommon. The shared IGH::BCL2 rearrangement is a robust finding in most transformed tumors underscoring that the cell of origin is perhaps a pre-B cell harboring IGH::BCL2 with the propensity to undergo further genetic alterations in the germinal centers of lymph nodes: does IGH::BCL2 in pre-B cells set off a plasticity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to BCL2 gene

Share to IGH gene

Share to Langerhans Cells

Share to Lymphoma, Follicular

Share to Mutation

Share to Myeloid Cells

Source

Identifiers

PMID: 38380864
DOI: 10.1080/10428194.2024.2319691

Genes

BCL2
IGH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potential genetic mechanisms driving B/myeloid conversion in patients with follicular lymphoma and Langerhans cell neoplasms.PMID 38380864Read ↗

Plasticity of Mature B Cells Between Follicular and Classic Hodgkin Lymphomas: A Series of 22 Cases Expanding the Spectrum of Transdifferentiation.Semantic proximity Read ↗

An updated understanding of follicular lymphoma transformationSemantic proximity Read ↗

The routes for transformation of follicular lymphoma.Semantic proximity Read ↗

Histological Transformation and Progression in Follicular Lymphoma: A Clonal Evolution Study.Semantic proximity Read ↗

B-cell lineage neoplasms transdifferentiating into histiocytic/dendritic cell neoplasms: diversity, differentiation lineage, genomic alterations, and therapy: Report from the 2021 SH/EAHP WorkshopSemantic proximity Read ↗

Follicular helper T-cell lymphomas: disease spectrum, relationship with clonal hematopoiesis, and mimics. A report of the 2022 EA4HP/SH lymphoma workshopSemantic proximity Read ↗

Transformation of follicular lymphoma.Semantic proximity Read ↗

Mutation landscape, clonal evolution pattern, and potential pathogenic pathways in B-lymphoblastic transformation of follicular lymphoma.Semantic proximity Read ↗

Nature and importance of follicular lymphoma precursorsSemantic proximity Read ↗

Biology as vulnerability in follicular lymphoma: genetics, epigenetics, and immunogeneticsSemantic proximity Read ↗

WHO classification of tumors of hematopoietic and lymphoid tissues, 2022 (5th edition): lymphoid tumorsSemantic proximity Read ↗

Transformation of Follicular Lymphoma to Precursor B-Cell Lymphoblastic Lymphoma With c-mycGene Rearrangement as a Critical EventSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.