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Article

Improving the resolution of canine genome-wide association studies using genotype imputation: A study of two breeds.

Animal genetics - 1 Oct 2021

Jenkins Christopher A, Schofield Ellen C, Mellersh Cathryn S, De Risio Luisa, Ricketts Sally L

Abstract excerpt

Genotype imputation using a reference panel that combines high-density array data and publicly available whole genome sequence consortium variant data is potentially a cost-effective method to increase the density of extant lower-density array datasets. In this study, three datasets (two Border Collie; one Italian Spinone) generated using a legacy array (Illumina CanineHD, 173 662 SNPs) were utilised to assess...

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PMID: 34252218
DOI: 10.1111/age.13117
PMCID: PMC8514152

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