Article
Assessment of the functionality of genome-wide canine SNP arrays and implications for canine disease association studies.
Animal genetics - 1 Apr 2011
Ke X, Kennedy L J, Short A D, Seppälä E H, Barnes A, Clements D N, Wood S H, Carter S D, Happ G M, Lohi H, Ollier W E R
Abstract excerpt
Domestic dogs share a wide range of important disease conditions with humans, including cancers, diabetes and epilepsy. Many of these conditions have similar or identical underlying pathologies to their human counterparts and thus dogs represent physiologically relevant natural models of human disorders. Comparative genomic approaches whereby disease genes can be identified in dog diseases and then mapped onto...
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