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Article

Tumor-Infiltrating Lymphocytes, Tumor Mutational Burden, and Genetic Alterations in Microsatellite Unstable, Microsatellite Stable, or Mutant POLE/POLD1 Colon Cancer.

JCO precision oncology - 1 Jan 2021

Keshinro Ajaratu, Vanderbilt Chad, Kim Jin K, Firat Canan, Chen Chin-Tung, Yaeger Rona, Ganesh Karuna, Segal Neil H, Gonen Mithat, Shia Jinru, Stadler Zsofia, Weiser Martin R

Abstract excerpt

To characterize the relationship between tumor-infiltrating lymphocytes (TIL), tumor mutational burden (TMB), and genetic alterations in microsatellite stable (MSS), microsatellite instability (MSI), or mutant POLE/POLD1 colon cancer. MATERIALS AND METHODS: Four hundred ninety-nine resected stage I-III colon tumors treated between 2014 and 2019 were assessed for TIL; somatic mutations, copy number alterations,...

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Identifiers

PMID: 34250404
DOI: 10.1200/PO.20.00456
PMCID: PMC8232557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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