Article
Association of NCF1 polymorphism with systemic lupus erythematosus and systemic sclerosis but not with ANCA-associated vasculitis in a Japanese population.
Scientific reports - 8 Nov 2019
Yokoyama Nozomi, Kawasaki Aya, Matsushita Takashi, Furukawa Hiroshi, Kondo Yuya, Hirano Fumio, Sada Ken-Ei, Matsumoto Isao, Kusaoi Makio, Amano Hirofumi, Nagaoka Shouhei, Setoguchi Keigo, Nagai Tatsuo, Shimada Kota, Sugii Shoji, Hashimoto Atsushi, Matsui Toshihiro, Okamoto Akira, Chiba Noriyuki, Suematsu Eiichi, Ohno Shigeru, Katayama Masao, Migita Kiyoshi, Kono Hajime, Hasegawa Minoru, Kobayashi Shigeto, Yamada Hidehiro, Nagasaka Kenji, Sugihara Takahiko, Yamagata Kunihiro, Ozaki Shoichi, Tamura Naoto, Takasaki Yoshinari, Hashimoto Hiroshi, Makino Hirofumi, Arimura Yoshihiro, Harigai Masayoshi, Sato Shinichi, Sumida Takayuki, Tohma Shigeto, Takehara Kazuhiko, Tsuchiya Naoyuki
Abstract excerpt
Genome-wide association studies of systemic lupus erythematosus (SLE) in Chinese and Korean populations demonstrated strong association of single nucleotide polymorphisms (SNPs) located in the GTF2I-NCF1 region, rs73366469 (GTF2I), rs117026326 (GTF2I), rs80346167(GTF2IRD1) and rs201802880 (NCF1). This region has also been associated with susceptibility to Sjögren syndrome and rheumatoid arthritis; however,...