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Article

HIV drug resistance prediction with weighted categorical kernel functions

30 Jul 2019

Abstract excerpt

BACKGROUND: Antiretroviral drugs are a very effective therapy against HIV infection. However, the high mutation rate of HIV permits the emergence of variants that can be resistant to the drug treatment. Predicting drug resistance to previously unobserved variants is therefore very important for an optimum medical treatment. In this paper, we propose the use of weighted categorical kernel functions to predict drug...

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PMID: 31362714
DOI: 10.1186/s12859-019-2991-2

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