Article
[Computational prediction of human immunodeficiency resistance to reverse transcriptase inhibitors].
Biomeditsinskaia khimiia - 1 Oct 2017
Tarasova O A, Filimonov D A, Poroikov V V
Abstract excerpt
Human immunodeficiency virus (HIV) causes acquired immunodeficiency syndrome (AIDS) and leads to over one million of deaths annually. Highly active antiretroviral treatment (HAART) is a gold standard in the HIV/AIDS therapy. Nucleoside and non-nucleoside inhibitors of HIV reverse transcriptase (RT) are important component of HAART, but their effect depends on the HIV susceptibility/resistance. HIV resistance...
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