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Article

Screening and identification of HLA-A2-restricted neoepitopes for immunotherapy of non-microsatellite instability-high colorectal cancer.

Science China. Life sciences - 1 Mar 2022

Shi Ranran, Li Yubing, Ran Ling, Dong Yu, Zhou Xiuman, Tang Jingwen, Han Lu, Wang Mingshuang, Pang Liwei, Qi Yuanming, Wu Yahong, Gao Yanfeng

Abstract excerpt

Colorectal cancer has one of the highest mortality rates among malignant tumors, and most patients with non-microsatellite instability-high (MSI-H) colorectal cancer do not benefit from targeted therapy or immune checkpoint inhibitors. Identification of immunogenic neoantigens is a promising strategy for inducing specific antitumor T cells for cancer immunotherapy. Here, we screened potential high-frequency...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 34236583
DOI: 10.1007/s11427-021-1944-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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