Article
Genetic evidence for a causative effect of airflow obstruction on left ventricular filling: a Mendelian randomisation study.
Respiratory research - 7 Jul 2021
Harbaum Lars, Hennigs Jan K, Simon Marcel, Oqueka Tim, Watz Henrik, Klose Hans
Abstract excerpt
BACKGROUND: Observational studies on the general population have suggested that airflow obstruction associates with left ventricular (LV) filling. To limit the influence of environmental risk factors/exposures, we used a Mendelian randomisation (MR) approach based on common genetic variations and tested whether a causative relation between airflow obstruction and LV filling can be detected. METHODS: We used...
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