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Article

Age at menarche and lung function: a Mendelian randomization study.

European journal of epidemiology - 1 Aug 2017

Gill Dipender, Sheehan Nuala A, Wielscher Matthias, Shrine Nick, Amaral Andre F S, Thompson John R, Granell Raquel, Leynaert Bénédicte, Real Francisco Gómez, Hall Ian P, Tobin Martin D, Auvinen Juha, Ring Susan M, Jarvelin Marjo-Riitta, Wain Louise V, Henderson John, Jarvis Deborah, Minelli Cosetta

Abstract excerpt

A trend towards earlier menarche in women has been associated with childhood factors (e.g. obesity) and hypothesised environmental exposures (e.g. endocrine disruptors present in household products). Observational evidence has shown detrimental effects of early menarche on various health outcomes including adult lung function, but these might represent spurious associations due to confounding. To address this we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28624884
DOI: 10.1007/s10654-017-0272-9
PMCID: PMC5591357

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