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Article

Association of Genetic Instrumental Variables for Lung Function on Coronary Artery Disease Risk: A 2-Sample Mendelian Randomization Study.

Circulation. Genomic and precision medicine - 1 Apr 2018

Au Yeung Shiu Lun, Borges Maria-Carolina, Lawlor Debbie A

Abstract excerpt

BACKGROUND: Lung function, assessed by forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC), is inversely associated with coronary artery disease (CAD), but these associations could be because of confounding or reversed causality. We conducted a 2-sample Mendelian randomization study, using publicly available data from relevant genome-wide association studies, to examine the role of FEV1 or...

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Identifiers

PMID: 29650766
DOI: 10.1161/CIRCGEN.117.001952

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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