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Article

A competing risks model with binary time varying covariates for estimation of breast cancer risks in BRCA1 families.

Statistical methods in medical research - 1 Sept 2021

Choi Yun-Hee, Jung Hae, Buys Saundra, Daly Mary, John Esther M, Hopper John, Andrulis Irene, Terry Mary Beth, Briollais Laurent

Abstract excerpt

Mammographic screening and prophylactic surgery such as risk-reducing salpingo oophorectomy can potentially reduce breast cancer risks among mutation carriers of BRCA families. The evaluation of these interventions is usually complicated by the fact that their effects on breast cancer may change over time and by the presence of competing risks. We introduce a correlated competing risks model to model breast and...

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Identifiers

PMID: 34232831
DOI: 10.1177/09622802211008945
PMCID: PMC8424615

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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