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Article

An RNA Transport System in Candida albicans Regulates Hyphal Morphology and Invasive Growth

25 Sept 2009

Abstract excerpt

Localization of specific mRNAs is an important mechanism through which cells achieve polarity and direct asymmetric growth. Based on a framework established in Saccharomyces cerevisiae, we describe a She3-dependent RNA transport system in Candida albicans, a fungal pathogen of humans that grows as both budding (yeast) and filamentous (hyphal and pseudohyphal) forms. We identify a set of 40 mRNAs that are...

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PMID: 19779551
DOI: 10.1371/journal.pgen.1000664

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