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Article

AgDD System: A Chemical Controllable Protein Aggregates in Cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Miyazaki Yusuke

Abstract excerpt

There are increasing evidence and growing interest in the relationship between protein aggregates/phase separation and various human diseases, especially neurodegenerative diseases. However, we do not entirely comprehend how aggregates generate or the clearance network of chaperones, proteasomes, ubiquitin ligases, and other factors interact with aggregates. Here, we describe chemically controllable systems...

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PMID: 34228296
DOI: 10.1007/978-1-0716-1441-9_16

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