Article
Angiogenesis' related genetic variants alter clinical features and prognosis of diffuse large B-cell lymphoma patients.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2021
Brito Angelo Borsarelli Carvalho, Delamain Marcia Torresan, Fanelli Marcello Ferreti, Soares Fernando Augusto, de Souza Cármino Antônio, Vassallo José, Lima Carmen Silvia Passos
Abstract excerpt
OBJECTIVES: Single nucleotide variants (SNVs) in vascular endothelial growth factor A (VEGFA) and VEGFA receptor (KDR) genes confer different inherited abilities in angiogenesis (AG) pathway. We aimed in the present study to evaluate influence of six VEGFA and four KDR SNVs in clinical features and survival of diffuse large B-cell lymphoma (DLBCL) patients. METHODS: One hundred and sixty-eight DLBCL patients...
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