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Article

Vascular endothelial growth factor A (VEGFA) gene polymorphisms have an impact on survival in a subgroup of indolent patients with chronic lymphocytic leukemia.

PloS one - 1 Jan 2014

Lozano-Santos Carol, Martinez-Velasquez Jimena, Fernandez-Cuevas Belen, Polo Natividad, Navarro Belen, Millan Isabel, Garcia Jose Miguel, Collado Rosa, Sanchez-Godoy Pedro, Carbonell Felix, Garcia-Vela Jose Antonio, Garcia-Marco Jose Antonio, Gomez-Lozano Natalia

Abstract excerpt

Vascular endothelial growth factor (VEGF)-mediated angiogenesis contributes to the pathogenesis of B-cell chronic lymphocytic leukaemia (CLL). We investigated the impact of VEGFA gene diversity on the clinical outcome of patients with this disease. A VEGFA haplotype conformed by positions rs699947 (-1540C>A), rs833061 (-460T>C) and rs2010963 (405C>G) and two additional single-nucleotide polymorphisms (SNPs),...

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Source

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Identifiers

PMID: 24971577
DOI: 10.1371/journal.pone.0101063
PMCID: PMC4074164

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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