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Article

Circulating cell-free DNA mutation patterns in early and late stage colon and pancreatic cancer.

Cancer genetics - 1 Dec 2017

Vietsch Eveline E, Graham Garrett T, McCutcheon Justine N, Javaid Aamir, Giaccone Giuseppe, Marshall John L, Wellstein Anton

Abstract excerpt

Cancer is a heterogeneous disease harboring diverse subclonal populations that can be discriminated by their DNA mutations. Environmental pressure selects subclones that ultimately drive disease progression and tumor relapse. Circulating cell-free DNA (ccfDNA) can be used to approximate the mutational makeup of cancer lesions and can serve as a marker for monitoring disease progression at the molecular level...

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Source

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Identifiers

PMID: 29153095
DOI: 10.1016/j.cancergen.2017.08.006
PMCID: PMC5726797

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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