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cfDNA Sequencing: Technological Approaches and Bioinformatic Issues

21 Jun 2021

Abstract excerpt

In the era of precision medicine, it is crucial to identify molecular alterations that will guide the therapeutic management of patients. In this context, circulating tumoral DNA (ctDNA) released by the tumor in body fluids, like blood, and carrying its molecular characteristics is becoming a powerful biomarker for non-invasive detection and monitoring of cancer. Major recent technological advances, especially in...

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PMID: 34205827
DOI: 10.3390/ph14060596

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