Predictive Value of miR-146a rs2431697 Polymorphism to Myelofibrosis Progression in Patients with Myeloproliferative Neoplasm.

doi:10.31557/APJCP.2021.22.11.3585

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Article

Predictive Value of miR-146a rs2431697 Polymorphism to Myelofibrosis Progression in Patients with Myeloproliferative Neoplasm.

Asian Pacific journal of cancer prevention : APJCP - 1 Nov 2021

Aref Salah, Atia Doaa, Al Tantawy Ahmed, Al Boghdady Mohamed, Gouda Enas

Abstract excerpt

BACKGROUND: Bone marrow myelofibrosis (BMF) that develop on top of Polycythaemia vera (PV) and essential thrombocythemia leads to shortening of the patient's overall survival. This study aimed to address the impact of miR-146a rs2431697 polymorphism on inflammatory biomarkers and genes expression and the hazards of myelofibrosis progression. PATIENTS AND METHODS: The study included 88 myeloproliferative neoplasm...

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PMID: 34837916
DOI: 10.31557/APJCP.2021.22.11.3585
PMCID: PMC9068196

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